Studies on the Health Benefits of Coffee
At Purity Coffee®, we are dedicated to examining evidence of the potential health benefits of coffee. Below are links to some prominent research studies that have been performed on the various health benefits of coffee use.
Alzheimers
- Followed 1,400 people over 20 years and found that those drinking 3–5 cups per day reduced their risk of being diagnosed with dementia or Alzheimer’s by 65%. (2009 Scandinavian study published in the Journal of Alzheimer’s Disease on coffee and dementia or Alzheimer’s)
Other notable studies on coffee and Alzheimer's
- Caffeine as a protective factor in dementia and Alzheimer’s disease - Journal of Alzheimer’s DiseaseTopic: Alzheimers
- Decaffeinated coffee prevents scopolamine-induced memory impairment in rats - Behavioural Brain Research/ElsevierTopic: Alzheimers
- Therapeutic Opportunities for Caffeine in Alzheimer’s Disease and Other Neurodegenerative Disorders - Journal of Alzheimer’s Disease Topic: Alzheimers
Breast Cancer
- Moderate to high consumption was associated with lower risk for breast cancer events in tamoxifen-treated patients with ERþ tumors (adjusted HR, 0.51; 95% confidence interval, 0.26–0.97). (Source: "Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer." Clinical Cancer Research 21.8 (2015): 1877-887)
Other notable studies on coffee and breast cancer
- Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer - Clinical Cancer ResearchTopic: Breast Cancer
- Coffee Consumption and Risk of Breast Cancer: An Up- To-Date Meta-Analysis - PLOS OneTopic: Breast Cancer
- Coffee Consumption Associated with Increased Mortality of Women with Breast Cancer - Journal of Caffeine ResearchTopic: Breast Cancer
- Coffee consumption modifies risk of estrogen-receptor negative breast cancer - Breast Cancer ResearchTopic: Breast Cancer
- Coffee prevents early events in tamoxifen-treated breast cancer patients and modulates hormone receptor status - Cancer Causes & ControlTopic: Breast Cancer
Depression
- Followed 50,000 women from the U.S. and Finland who were initially free of depression for as long as 24 years (in some cases but not all), and found that women drinking 4+ cups/day reduced their risk of depression by 20% – drinking decaf or other caffeinated drinks was found to have nearly zero benefit. (NIH-supported study published in 2011 and conducted by the Department of Nutrition at the Harvard School of Public Health on depression and coffee in women)
- Followed 86,000 nurses over the course of 10 years and found women drinking 4+ cups/day reduced their risk of committing suicide by more than half. (Study published in 1996 by the Journal of the American Medical Association on women and risk of suicide)
Other notable studies on coffee and depression:
- Rosmarinic acid and caffeic acid produce antidepressive-like effect in the forced swimming test in mice - European Journal of PharmacologyTopic: Depression
Enhanced Performance
- Coffee Consumption and Cognitive Function among Older Adults - American Journal of Epidemiology/Oxford University PressTopic: Enhance Performance
- Effect of caffeinatedcoffee on running speed, respiratoryfactors,blood lactateand perceived exertionduring 1500-r treadmillrunning - British Journal of Sports MedicineTopic: Enhance Performance
Enhanced Metabolism
- Habitual coffee but not green tea consumption is inversely associated with metabolic syndrome - Diabetes Research and Clinical Practice/ElsevierTopic: Enhanced Metabolism
Gallstones
- Followed almost 90,000 women over 30 years and found those drinking 2-3 cups of caffeinated coffee/day had a 22% lower risk of developing gallstones. (Source: Study published in 2002 from the Nurse’s Health Study on coffee and gallstones in women)
Heart Disease
- Followed 40,000+ male health professionals over 18 years and found men drinking 5+ cups/day reduced their risk of dying from heart disease by 44%. (Source: 2008 Nurse’s Health Study published in the Annals of Internal Medicine on coffee & heart disease)
Other notable studies on coffee and heart disease
- Cholesterol-raising diterpenes in types of coffee commonly consumed in Singapore, Indonesia and India and associations with blood lipids: A survey and cross sectional study - Nutrition JournalTopic: Heart Disease
- Coffee and Health: A Review of Recent Human Research - Critical Reviews in Food Science and Nutrition/Taylor & FrancisTopic: Heart Disease
- Coffee Consumption and Cardiovascular Health: Getting to the Heart of the Matter - Ischemic Heart DiseaseTopic: Heart Disease
- Consumption of coffee is associated with reduced risk of death attributed to inflammatory and cardiovascular diseases in the Iowa Women’s Health Study1– 4 - American Journal of Clinical Nutrition/American Society for NutritionTopic: Heart Disease
- Effects of caffeine on human health - Food Additives and Contaminantes/TAYLOR AND FRANCISTopic: Heart Disease
Improved Brain Function
- Coffee Consumption and Cognitive Function among Older Adults - American Journal of Epidemiology/Oxford University PressTopic: Improved Brain Function
Life Expectancy
- Surveyed 400,000 people over 14 years and found the overall mortality rate of those drinking 2-6 cups/day was reduced by 10% for men and 15% for women. (Source: 2012 National Institutes of Health study published in the New England Journal of Medicine on coffee and mortality rates)
Other notable studies on coffee and longevity
- Association of Coffee Consumption with Total and Cause-Specific Mortality in Three Large Prospective Cohorts - Circulation/American Heart AssociationTopic: Life Expectancy
- Association of Coffee Drinking with Total and Cause-Specific Mortality - New England Journal of MedicineTopic: Life Expectancy
- Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans - Longevity & HealthspanTopic: Life Expectancy
- Consumption of coffee is associated with reduced risk of death attributed to inflammatory and cardiovascular diseases in the Iowa Women’s Health Stud - American Journal of Clinical Nutrition/American Society for NutritionTopic: Life Expectancy
Liver Disease
- Surveyed approx. 240,000 people (2,260 people had been diagnosed with liver disease) and found that the likelihood of developing liver disease for people who drank coffee vs. those who didn’t dropped by 23% with each daily cup. (Source: Hepatology journal reported in 2007 on 10 studies conducted in Europe & Asia on coffee & liver disease)
- Found regular coffee consumption could reduce risk of developing hepatocellular carcinoma by about 40% and could be as much as 50% for those drinking 3+ cups/day. (Source: "Coffee Reduces Risk for Hepatocellular Carcinoma: An Updated Meta-analysis." Clinical Gastroenterology and Hepatology 11.11 (2013): 1414-1421 – 2013 Italian meta-analysis of 16 studies published in Clinical Gastroenterology and Hepatology on coffee & hepatocellular carcinoma (most common form of liver cancer))
Other notable studies on coffee and liver disease
- Coffee and Health: A Review of Recent Human Research - Critical Reviews in Food Science and Nutrition/Taylor & FrancisTopic: Liver Cancer
- Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C - HepatologyTopic: Liver Cancer
- Furan in Coffee Products: A Probabilistic Exposure Estimation - Coffee in Health and Disease Prevention (Book)Topic: Liver Cancer
- Species, roasting degree and decaffeination influence the antibacterial activity of coffee against Streptococcus mutans - Food ChemistryTopic: Liver Cancer
- Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis - Alimentary Pharmacology and TherapeuticsTopic: Liver Cancer
Parkinson's
- Followed 8,004 participants in the Honolulu Heart Program for 30 years and found that people who did not drink coffee had 5 times more risk of eventually being diagnosed with Parkinson’s than those who consumed 3+ cups/day. (Source: 2000 study published in Journal of the American Medical Association on Parkinson’s and coffee)
- Found that regularly drinking 3+ cups/day reduces the chance of getting Parkinson’s by 25%, and drinking more further reduces the risk. (Source: 2010 meta-analysis of 26 studies by the Center for Evidence-Based Medicine at the University of Lisbon on coffee and Parkinson’s (didn’t say how many people in studies collectively or the total amount of time))
Other notable studies on coffee and Parkinson's
- Tobacco, coffee, and Parkinson’s disease - National Center for Biotechnology InformationTopic: Parkinsons
- Coffee and Health: A Review of Recent Human Research - Critical Reviews in Food Science and Nutrition/Taylor & FrancisTopic: Parkinsons
- Decaffeinated coffee prevents scopolamine-induced memory impairment in rats - Behavioural Brain Research/ElsevierTopic: Parkinsons
Prostate Cancer
- A 2009 study closely surveyed 50,000 male health professionals over 20 years and found that those drinking 6+ cups per day reduced their chances of developing advanced prostate cancer by 60%. 3 cups reduced risk by 20% and 4-5 cups reduced risk by 25%. (Source: 2009 study funded by National Institutes of Health on drinking coffee & prostate cancer)
Other notable studies on coffee and prostate cancer:
- Furan in Coffee Products: A Probabilistic Exposure Estimation - Coffee in Health and Disease Prevention (Book)Topic: Prostate Cancer
Stroke
- Followed 83,000 women over 24 years and found that women who drank 2+ cups/day reduced their risk of stroke by 19% with a greater reduction the more they drank – non-smoking women who drank 4+ cups/day reduced the risk of stroke by 43%. (Source: A Harvard study done with researchers from the Universidad Autonoma de Madrid using data from a Nurse’s Health Study (no date was mentioned for publication) on coffee & strokes in women)
Other notable studies on coffee and reduced risk of stroke:
- Consumption of coffee is associated with reduced risk of death attributed to inflammatory and cardiovascular diseases in the Iowa Women’s Health Stud - American Journal of Clinical Nutrition/American Society for NutritionTopic: Stroke
- Coffee and Health: A Review of Recent Human Research - Critical Reviews in Food Science and Nutrition/Taylor & FrancisTopic: Stroke
- Cholesterol-raising diterpenes in types of coffee commonly consumed in Singapore, Indonesia and India and associations with blood lipids: A survey and cross sectional study - Nutrition JournalTopic: Stroke
- Coffee Consumption and Cardiovascular Health: Getting to the Heart of the Matter - Ischemic Heart DiseaseTopic: Stroke
Type II Diabetes
- A meta analysis on 28 scientific studies combined representing over 1.1 million participants over more than 20 years showed your risk of developing type two diabetes goes down 9% for every cup of coffee you drink. (Source: "Caffeinated and Decaffeinated Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review and a Dose-Response Meta-analysis." Diabetes Care 37.2 (2014): 569-86)
- Surveyed 125,000 people over 18 years and found that men who drank 6+ cups/daily reduced their risk of being diagnosed with adult-onset diabetes by 54%, and women drinking the same amount reduced their chances by 30%. (Source: 2004 study published in Annals of Internal Medicine from researchers at Harvard School of Public Health and Brigham and Women’s Hospital on coffee & type II diabetes)
Other notable studies on coffee and T2D
- Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis. - Diabetes CareTopic: Diabetes
- Beverage Intake, Diabetes, and Glucose Control of Adults in America - Annals of Epidemiology/ElsevierTopic: Diabetes
- Changes in coffee intake and subsequent risk of type 2 diabetes: three large cohorts of US men and women - Diabetologia/SpringerTopic: Diabetes
- Coffee and Health: A Review of Recent Human Research - Critical Reviews in Food Science and Nutrition/Taylor & FrancisTopic: Diabetes
- Coffee Consumption and Cardiovascular Health: Getting to the Heart of the Matter - Ischemic Heart DiseaseTopic: Diabetes
- Coffee drinking induces incorporation of phenolic acids into LDL and increases the resistance of LDL to ex vivo oxidation in humans - American Journal of Clinical Nutrition/American Society for NutritionTopic: Diabetes
- Coffee, tea and diabetes: the role of weight loss and caffeine - International Journal of ObesityTopic: Diabetes
- Oxidative Stress and Antioxidant Treatment in Diabetes - Annals of the New York Academy of SciencesTopic: Diabetes